Function of Red peony root extract

1. red peony extract has significant analgesic, sedative and anticonvulsant effects. Peony extract can antagonize the convulsion caused by Shi Ning. Intraperitoneal injection of mice has significant analgesic effects, and analgesic effects may not be related to mor--phine receptors. It can prolong the sleep time of sodium phen-obarbital in mice and antagonize the convulsion caused by pentaerythritol.
2. red peony extract can expand coronary arteries, increase coronary flow, fight acute myocardial ischemia, and lower blood pressure.
3. The effect of paeoniflorin on blood-brain barrier and neuropathological changes of cerebral ischemia and cerebral blood flow during cerebral ischemia and reperfusion. Paeoniflorin was found to have protective effects on cerebral edema, blood-brain barrier and local blood flow in the brain after cerebral ischemia. Paeoniflorin in patients with focal cerebral ischemia can significantly reduce the degree of cerebral edema, reduce the scope of cerebral infarction, improve neurobehavioral symptoms, blood-brain barrier permeability, and increase local blood flow in the brain. It shows obvious protective effect on focal cerebral ischemia injury, and its protective mechanism may be related to the following factors; inhibiting intracellular calcium overload, anti-free radical, cerebral vasoconstriction dysfunction caused by ischemia and hypoxia A good improvement effect has a protective effect on the blood-brain barrier during cerebral ischemia and reperfusion, and can promote the recovery of cerebral blood flow in the early stage of reperfusion.
4. Intravenous injection of paeoniflorin can significantly reduce the blood glucose of streptozotocin-induced diabetic mice, and the sugar content in plasma also decreases with the prolongation of medication time.
5. red peony extract can stimulate plasma fibronectin in rats, promote its blood level and promote the function of reticuloendothelial system. Prophylaxis of paeoniflorin for 7 consecutive days can significantly increase serum alanine aminotransferase, decrease serum albumin and decrease hepatic glycogen content after liver injury induced by D-galactosamine or carbon tetrachloride in mice. Learning liver cell degeneration and necrosis have been significantly improved and restored. Paeoniflorin also inhibits ethanol-induced elevation of serum transaminases.